BDBM50208006 3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-di-(4-fluorophenyl)-imidazolidin-2-one::CHEMBL221401

SMILES Fc1ccc(cc1)C1(CN(C2CCN(Cc3cccc(F)c3)CC2)C(=O)N1)c1ccc(F)cc1

InChI Key InChIKey=HWCBLDPYKRZMKJ-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50208006   

TargetCytochrome P450 1A2(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208006(3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP1A2 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208006(3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human CYP2D6 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208006(3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208006(3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of human CYP2C19 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208006(3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human CYP2C9 expressed in insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208006(3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataKi:  4.83nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human muscarinic M3 receptor expressed in CHO K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Via Zambeletti 25

Curated by ChEMBL
LigandPNGBDBM50208006(3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-di-(4-fl...)
Affinity DataKi:  1.14E+3nMAssay Description:Displacement of [3H]N-methyl-scopolamine from human muscarinic M2 receptor expressed in CHO K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed