BDBM50207579 CHEMBL232838::N-{3-methanesulfonyl-4-[4-(5-nitro-1H-benzoimidazol-2-yl)-phenylsulfanylmethyl]-benzoyl}-guanidine

SMILES CS(=O)(=O)c1cc(ccc1CSc1ccc(cc1)-c1nc2ccc(cc2[nH]1)[N+]([O-])=O)C(=O)NC(N)=N

InChI Key InChIKey=VYJVZYXSHRLTRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207579   

TargetSodium/hydrogen exchanger 1(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207579(N-{3-methanesulfonyl-4-[4-(5-nitro-1H-benzoimidazo...)
Affinity DataIC50: 27.8nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed