BDBM50207505 1-(4-(3-amino-7-(2-(diethylamino)ethoxy)-1H-indazol-4-yl)phenyl)-3-m-tolylurea::CHEMBL219774::N-{4-[3-amino-7-(2-diethylaminoethoxy)-1H-indazol-4-yl]-phenyl}-N'-(3-methylphenyl)urea

SMILES CCN(CC)CCOc1ccc(-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)c2c(N)n[nH]c12

InChI Key InChIKey=ILTQFFVJLSZIER-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50207505   

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207505(1-(4-(3-amino-7-(2-(diethylamino)ethoxy)-1H-indazo...)
Affinity DataIC50: 61nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207505(1-(4-(3-amino-7-(2-(diethylamino)ethoxy)-1H-indazo...)
Affinity DataIC50: 35nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207505(1-(4-(3-amino-7-(2-(diethylamino)ethoxy)-1H-indazo...)
Affinity DataIC50: 60nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207505(1-(4-(3-amino-7-(2-(diethylamino)ethoxy)-1H-indazo...)
Affinity DataIC50: 61nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed