BDBM50207503 1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(3-fluoro-4-methylphenyl)urea::CHEMBL426004::N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(3-fluoro-4-methylphenyl)urea

SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)cc1F

InChI Key InChIKey=OJDNHAXBNCOFRF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50207503   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207503(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(3-fluoro-...)
Affinity DataIC50: 48nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207503(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(3-fluoro-...)
Affinity DataIC50: 48nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207503(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(3-fluoro-...)
Affinity DataIC50: 42nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207503(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(3-fluoro-...)
Affinity DataIC50: 47nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207503(1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(3-fluoro-...)
Affinity DataIC50: 42nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed