BDBM50207487 1-(4-(3-amino-7-(2-morpholinoethoxy)-1H-indazol-4-yl)phenyl)-3-m-tolylurea::CHEMBL223478::N-{4-[3-amino-7-(2-morpholin-4-ylethoxy)-1H-indazol-4-yl]-phenyl}-N'-(3-methylphenyl)urea

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2ccc(OCCN3CCOCC3)c3[nH]nc(N)c23)c1

InChI Key InChIKey=GRFMNFFXDFTYNV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50207487   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207487(N-{4-[3-amino-7-(2-morpholin-4-ylethoxy)-1H-indazo...)
Affinity DataIC50: 21nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207487(N-{4-[3-amino-7-(2-morpholin-4-ylethoxy)-1H-indazo...)
Affinity DataIC50: 56nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207487(N-{4-[3-amino-7-(2-morpholin-4-ylethoxy)-1H-indazo...)
Affinity DataIC50: 24nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207487(N-{4-[3-amino-7-(2-morpholin-4-ylethoxy)-1H-indazo...)
Affinity DataIC50: 50nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207487(N-{4-[3-amino-7-(2-morpholin-4-ylethoxy)-1H-indazo...)
Affinity DataIC50: 50nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed