BDBM50207484 1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-o-tolylurea::CHEMBL376077::N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-methylphenyl)-urea

SMILES Cc1ccccc1NC(=O)Nc1ccc(cc1)-c1cccc2[nH]nc(N)c12

InChI Key InChIKey=XTKIFGMBONJHTF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50207484   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207484(N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-methyl...)
Affinity DataIC50: 80nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207484(N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-methyl...)
Affinity DataIC50: 87nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207484(N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-methyl...)
Affinity DataIC50: 86nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207484(N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-methyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207484(N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-methyl...)
Affinity DataIC50: 86nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed