BDBM50207477 1-(4-(3-amino-7-(2-(2-oxopyrrolidin-1-yl)ethoxy)-1H-indazol-4-yl)phenyl)-3-m-tolylurea::CHEMBL376245::N-(4-{3-amino-7-[2-(2-oxopyrrolidin-1-yl)ethoxy]-1H-indazol-4-yl}phenyl)-N'-(3-methylphenyl)urea

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2ccc(OCCN3CCCC3=O)c3[nH]nc(N)c23)c1

InChI Key InChIKey=LXNNTWRSZCNLBX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50207477   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207477(1-(4-(3-amino-7-(2-(2-oxopyrrolidin-1-yl)ethoxy)-1...)
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207477(1-(4-(3-amino-7-(2-(2-oxopyrrolidin-1-yl)ethoxy)-1...)
Affinity DataIC50: 53nMAssay Description:Inhibition of c-Kit by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207477(1-(4-(3-amino-7-(2-(2-oxopyrrolidin-1-yl)ethoxy)-1...)
Affinity DataIC50: 15nMAssay Description:Inhibition of FLT3 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50207477(1-(4-(3-amino-7-(2-(2-oxopyrrolidin-1-yl)ethoxy)-1...)
Affinity DataIC50: 53nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed