BDBM50207402 CHEMBL3980125

SMILES CCCc1c(OCc2cccc(Oc3ncccc3-c3nn[nH]n3)c2)ccc(C(C)=O)c1O

InChI Key InChIKey=SJYPGLAXMLBTJM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207402   

TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207402(CHEMBL3980125)
Affinity DataEC50:  227nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207402(CHEMBL3980125)
Affinity DataIC50: 390nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed