BDBM50207363 CHEMBL3898282

SMILES CN(Cc1ccncc1N(CC=C)S(C)(=O)=O)c1nc(Nc2ccc(N3CCOCC3)c(Br)c2)ncc1C(F)(F)F

InChI Key InChIKey=NBNLWEDCHCWEGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207363   

TargetFocal adhesion kinase 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207363(CHEMBL3898282)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207363(CHEMBL3898282)
Affinity DataIC50: 6.63E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed