BDBM50207355 CHEMBL3987106

SMILES CS(=O)(=O)N1CCCc2cc(Nc3ncc(c(NCc4cccnc14)n3)C(F)(F)F)ccc2N1CCOCC1

InChI Key InChIKey=BHHAWDHWFJBPHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207355   

TargetProtein-tyrosine kinase 2-beta(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207355(CHEMBL3987106)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207355(CHEMBL3987106)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed