BDBM50207331 CHEMBL3980735

SMILES Clc1cc2nc(N3CCC(CC3)C(=O)N[C@@H]3CCOC3)n(-c3ccc4ccccc4n3)c2cc1Cl

InChI Key InChIKey=RYYMPUGIWWGTCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207331   

TargetProstaglandin E synthase(Human)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50207331(CHEMBL3980735)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant membrane bound mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 by measuring MDA and 12-HHT formation by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed