BDBM50207320 CHEMBL3918689

SMILES Cc1cc2c3[nH]c(Nc4c(F)cccc4Cl)nc3cc(C(=O)Nc3ccc(F)cc3)c2o1

InChI Key InChIKey=BLQDUSDPNMSKRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207320   

TargetProstaglandin E synthase(Human)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50207320(CHEMBL3918689)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50207320(CHEMBL3918689)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed