BDBM50206985 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE::2-(5-chlorothiophen-2-yl)-N-((S)-1-((S)-1-morpholino-1-oxopropan-2-yl)-2-oxopyrrolidin-3-yl)ethanesulfonamide::CHEMBL391737

SMILES C[C@@H](C(=O)N1CCOCC1)N2CC[C@@H](C2=O)NS(=O)(=O)CCc3ccc(s3)Cl

InChI Key InChIKey=IAUZEBLXCOCAFL-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50206985   

TargetPlasminogen(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of plasmin by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of tissue plasminogen activator by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of activated protein C by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of kallikrein by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataKi:  17nMAssay Description:Inhibition of thrombin by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataKi:  17nMAssay Description:Inhibition of thrombin by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206985(2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-...)
Affinity DataKi:  154nMAssay Description:Inhibition of factor 10a by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed