BDBM50206756 CHEMBL3950161

SMILES COc1ccc(Br)c(CC2CCN(CCc3ccc(OC)c(Cl)c3)CC2)c1

InChI Key InChIKey=MIDCNXRJVLYQEW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206756   

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50206756(CHEMBL3950161)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

Curated by ChEMBL
LigandPNGBDBM50206756(CHEMBL3950161)
Affinity DataKi:  19nMAssay Description:Inhibition of human SERT expressed in CHO cell membranes assessed as reduction in [3H]serotonin uptake preincubated for 10 mins followed by [3H]serot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed