BDBM50206613 3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzoic acid::4-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzoic acid::CHEMBL219673

SMILES OC(=O)c1cccc(NC(=O)COc2ccc(cc2)C23CC4CC(CC(C4)C2)C3)c1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50206613   

TargetHypoxia-inducible factor 1-alpha(Human)
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50206613(3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzo...)
Affinity DataIC50: 350nMAssay Description:Inhibition of hypoxia induced HIF1-alpha transcriptional activity in human AGS cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Molecular Cancer Research Center

Curated by ChEMBL
LigandPNGBDBM50206613(3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzo...)
Affinity DataIC50: 400nMAssay Description:Inhibition of hypoxia induced HIF1-alpha transcriptional activity in human Hep3B cells by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50206613(3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzo...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed