BDBM50206423 4-(5-(4-fluorophenyl)-3-isopropylisoxazol-4-yl)pyridine::4-[5-(4-fluorophenyl)-3-isopropylisoxazol-4-yl]pyridine::5-(4-fluorophenyl)-3-isopropyl-4-(pyridin-4-yl)isoxazole::CHEMBL375428

SMILES CC(C)c1noc(c1-c1ccncc1)-c1ccc(F)cc1

InChI Key InChIKey=AAQCZWGHNUPNMG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50206423   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50206423(4-(5-(4-fluorophenyl)-3-isopropylisoxazol-4-yl)pyr...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of p38-alpha MAPK by non-radioactive immunosorbent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50206423(4-(5-(4-fluorophenyl)-3-isopropylisoxazol-4-yl)pyr...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of JNK3 by non-radioactive immunosorbent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50206423(4-(5-(4-fluorophenyl)-3-isopropylisoxazol-4-yl)pyr...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50206423(4-(5-(4-fluorophenyl)-3-isopropylisoxazol-4-yl)pyr...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50206423(4-(5-(4-fluorophenyl)-3-isopropylisoxazol-4-yl)pyr...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of p38alpha by Cherenkov countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed