BDBM50206391 CHEMBL3894492

SMILES COc1ccc(cc1)S(=O)(=O)Nc1ccc2[nH]nc(-c3cccc(NC(=O)\C=C/C(O)=O)c3)c2c1

InChI Key InChIKey=GCACJMCPQBNCGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206391   

TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50206391(CHEMBL3894492)
Affinity DataIC50: 480nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50206391(CHEMBL3894492)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed