BDBM50206334 CHEMBL397686::Diphenylene iodonium chloride::dibenziodolium chloride

SMILES [I+]1c2ccccc2-c2ccccc12

InChI Key InChIKey=QFXKXRXFBRLLPQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206334   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Harvard School of Public Health

Curated by ChEMBL
LigandPNGBDBM50206334(Diphenylene iodonium chloride | dibenziodolium chl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum DHODMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (fumarate)(Baker's yeast)
Harvard School of Public Health

Curated by ChEMBL
LigandPNGBDBM50206334(Diphenylene iodonium chloride | dibenziodolium chl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Saccharomyces cerevisiae DHODMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNADPH oxidase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50206334(Diphenylene iodonium chloride | dibenziodolium chl...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human NOX1 expressed in CHO cells assessed as inhibition of PMA-induced hydrogen peroxide production pretreated for 15 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCytochrome b-245 heavy chain(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50206334(Diphenylene iodonium chloride | dibenziodolium chl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of NOX2 in human PLB-985 cells assessed as inhibition of PMA-induced hydrogen peroxide production pretreated for 15 mins followed by PMA s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNADPH oxidase 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50206334(Diphenylene iodonium chloride | dibenziodolium chl...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human NOX4 expressed in HEK293T cells assessed as inhibition of teracycline-induced hydrogen peroxide production pretreated for 18 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNADPH oxidase 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50206334(Diphenylene iodonium chloride | dibenziodolium chl...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human NOX5 expressed in HEK293 cells assessed as inhibition of ionomycin-induced hydrogen peroxide production pretreated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed