BDBM50206277 4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-(methylamino)ethyl)phenyl)pyrimidin-2-amine::CHEMBL393460

SMILES CNCCc1ccc(Nc2ncc(Cl)c(n2)-c2ccc(cc2)C(C)(C)N)cc1

InChI Key InChIKey=VZLVPTSUFJDRRQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206277   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206277(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206277(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloro-N-(4-(2-...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed