BDBM50206197 CHEMBL235565::methyl 2-(2-(4-formylphenoxy)acetamido)-3-(1H-indol-3-yl)propanoate

SMILES COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)COc1ccc(C=O)cc1

InChI Key InChIKey=RUDNBTRMIBMJNB-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50206197   

TargetCarboxylic ester hydrolase(Horse)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50206197(methyl 2-(2-(4-formylphenoxy)acetamido)-3-(1H-indo...)
Affinity DataIC50: 3.39E+4nMAssay Description:Inhibition of BuChE in horse serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Pacific electric ray)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50206197(methyl 2-(2-(4-formylphenoxy)acetamido)-3-(1H-indo...)
Affinity DataIC50: 280nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50206197(methyl 2-(2-(4-formylphenoxy)acetamido)-3-(1H-indo...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of mashroom tyrosinase assessed as oxidation of L-DOPA by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50206197(methyl 2-(2-(4-formylphenoxy)acetamido)-3-(1H-indo...)
Affinity DataKi:  5.40E+4nMAssay Description:Inhibition of mushroom tyrosinase assessed as oxidation of L-DOPA by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed