BDBM50206153 CHEMBL246032::N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)quinoline-3-carboxamide::N-(2-(4-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)quinoline-3-carboxamide::cid_44438309

SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cnc2ccccc2c1

InChI Key InChIKey=QYXQSMNQBJSTTJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50206153   

TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206153(cid_44438309 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50: 42nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206153(cid_44438309 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50: 160nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206153(cid_44438309 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50: 59nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206153(cid_44438309 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50: 8nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206153(cid_44438309 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50: 600nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206153(cid_44438309 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50: 42nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50206153(cid_44438309 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed