BDBM50206079 CHEMBL233229::N-[2-(1-benzyl-piperidin-4-ylamino)-benzothiazol-5-yl]-thiophene-2-carboxamidine

SMILES NC(=Nc1ccc2sc(NC3CCN(Cc4ccccc4)CC3)nc2c1)c1cccs1

InChI Key InChIKey=WIXPEYLZXBBVCS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50206079   

TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206079(N-[2-(1-benzyl-piperidin-4-ylamino)-benzothiazol-5...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human endothelial NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206079(N-[2-(1-benzyl-piperidin-4-ylamino)-benzothiazol-5...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human inducible NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206079(N-[2-(1-benzyl-piperidin-4-ylamino)-benzothiazol-5...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human neuronal NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed