BDBM50206076 CHEMBL234498::N-{2-[1-(4-methoxy-benzyl)-piperidin-4-ylamino]-benzothiazol-6-yl}-thiophene-2-carboxamidine

SMILES COc1ccc(CN2CCC(CC2)Nc2nc3ccc(cc3s2)N=C(N)c2cccs2)cc1

InChI Key InChIKey=JKCMRFBLPLIHBN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50206076   

TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206076(N-{2-[1-(4-methoxy-benzyl)-piperidin-4-ylamino]-be...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human endothelial NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206076(N-{2-[1-(4-methoxy-benzyl)-piperidin-4-ylamino]-be...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human neuronal NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206076(N-{2-[1-(4-methoxy-benzyl)-piperidin-4-ylamino]-be...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human inducible NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed