BDBM50206075 4-(4-{6-[(thiophene-2-carboximidoyl)-amino]-benzothiazol-2-ylamino}-piperidin-1-ylmethyl)-benzoic acid methyl ester::CHEMBL397710

SMILES COC(=O)c1ccc(CN2CCC(CC2)Nc2nc3ccc(cc3s2)N=C(N)c2cccs2)cc1

InChI Key InChIKey=FHFNDIVJRLHNNN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50206075   

TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206075(4-(4-{6-[(thiophene-2-carboximidoyl)-amino]-benzot...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human inducible NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206075(4-(4-{6-[(thiophene-2-carboximidoyl)-amino]-benzot...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human endothelial NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206075(4-(4-{6-[(thiophene-2-carboximidoyl)-amino]-benzot...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human neuronal NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed