BDBM50206068 CHEMBL233654::N-(2-{1-[2-(4-Bromo-phenyl)-ethyl]-piperidin-4-ylamino}-benzothiazol-6-yl)-thiophene-2-carboxamidine

SMILES NC(=Nc1ccc2nc(NC3CCN(CCc4ccc(Br)cc4)CC3)sc2c1)c1cccs1

InChI Key InChIKey=ACTRHEQNZRHTRP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50206068   

TargetNitric oxide synthase, brain(Rat)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206068(N-(2-{1-[2-(4-Bromo-phenyl)-ethyl]-piperidin-4-yla...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of rat neuronal NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206068(N-(2-{1-[2-(4-Bromo-phenyl)-ethyl]-piperidin-4-yla...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human neuronal NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206068(N-(2-{1-[2-(4-Bromo-phenyl)-ethyl]-piperidin-4-yla...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of human inducible NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206068(N-(2-{1-[2-(4-Bromo-phenyl)-ethyl]-piperidin-4-yla...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human endothelial NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Rat)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206068(N-(2-{1-[2-(4-Bromo-phenyl)-ethyl]-piperidin-4-yla...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of rat endothelial NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed