BDBM50206066 CHEMBL233653::N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl]-piperidin-4-ylamino}-benzothiazol-6-yl)-thiophene-2-carboxamidine

SMILES NC(=Nc1ccc2nc(NC3CCN(CCc4cnc[nH]4)CC3)sc2c1)c1cccs1

InChI Key InChIKey=AJUMWQHTJSVBPG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206066   

TargetNitric oxide synthase, inducible(Rat)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206066(N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl]-piperidin-4-y...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of rat inducible NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206066(N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl]-piperidin-4-y...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human inducible NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206066(N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl]-piperidin-4-y...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human endothelial NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206066(N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl]-piperidin-4-y...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human neuronal NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Rat)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206066(N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl]-piperidin-4-y...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of rat endothelial NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50206066(N-(2-{1-[2-(3H-imidazol-4-yl)-ethyl]-piperidin-4-y...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of rat neuronal NOS activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed