BDBM50205819 CHEMBL3978462

SMILES C[C@H]1CC(=O)Nc2ccc(c(CN(C)C(=O)[C@H](Nc3ccc4c(N)ncc(F)c4c3)c3ccc(OCC(F)F)c1c3)c2)S(=O)(=O)C1CC1

InChI Key InChIKey=UWAQLEGUXYPPDC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50205819   

TargetKallikrein-1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50205819(CHEMBL3978462)
Affinity DataKi:  23nMAssay Description:Inhibition of tissue Kallikrein-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetCoagulation factor VII/Tissue factor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50205819(CHEMBL3978462)
Affinity DataKi:  67nMAssay Description:Inhibition of recombinant human factor-7a/TF using S2288 as substrate measured after 60 mins at 37 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50205819(CHEMBL3978462)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibition of activated protein C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed