BDBM50205815 CHEMBL3907670

SMILES Oc1cccc2O\C(=C/c3ccc(=O)n(O)c3)C(=O)c12

InChI Key InChIKey=HQOPRQNMXIQDMF-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50205815   

TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205815(CHEMBL3907670)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of tyrosinase in human MNT1 cells assessed as suppression of melanin biosynthesis measured after 96 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205815(CHEMBL3907670)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of tyrosinase in human MNT1 cell lysate pretreated prior to addition of L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205815(CHEMBL3907670)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205815(CHEMBL3907670)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205815(CHEMBL3907670)
Affinity DataKi:  1.02E+3nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205815(CHEMBL3907670)
Affinity DataKi:  1.02E+3nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205815(CHEMBL3907670)
Affinity DataKi:  1.02E+3nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed