BDBM50205814 CHEMBL3898657

SMILES Oc1cccc[n+]1[O-]

InChI Key InChIKey=JVHZMYAXZUIZKS-UHFFFAOYSA-N

Data  7 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50205814   

TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of tyrosinase in human MNT1 cells assessed as suppression of melanin biosynthesis measured after 96 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataIC50: 1.30E+6nMAssay Description:Inhibition of tyrosinase in human MNT1 cell lysate pretreated prior to addition of L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of tyrosinase in mouse B16-F10 cells assessed as inhibition of melanin production measured after 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataIC50: 1.30E+6nMAssay Description:Inhibition of tyrosinase in human MNT-1 cell lysates assessed as inhibition of melanin production using L-DOPA as substrate measured after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of tyrosinase in human MNT-1 cells assessed as inhibition of melanin production measured after 96 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  1.80E+3nMAssay Description:Competitive inhibition of Agaricus bisporus tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  1.80E+3nMAssay Description:Competitive inhibition of Agaricus bisporus tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Streptomyces antibioticus)
University of Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  7.70E+3nMAssay Description:Competitive inhibition of Streptomyces antibioticus tyrosinase using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  1.28E+5nMAssay Description:Inhibition of recombinant human tyrosinase expressed in baculovirus infected Sf9 cells assessed as diphenolase activity using L-DOPA as substrate by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2018
Entry Details Article
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  1.28E+5nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  1.28E+5nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
Univ. Grenoble-Alpes/Cnrs

Curated by ChEMBL
LigandPNGBDBM50205814(CHEMBL3898657)
Affinity DataKi:  1.28E+5nMAssay Description:Competitive inhibition of human recombinant tyrosinase expressed in Sf9 cells using L-DOPA as substrate by Michelis-Menten based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed