BDBM50205789 (E)-5-(4-fluorostyryl)-2-(4-fluorophenylsulfonyl)pyridine::CHEMBL240840

SMILES Fc1ccc(\C=C\c2ccc(nc2)S(=O)(=O)c2ccc(F)cc2)cc1

InChI Key InChIKey=BPSGUTHNLYFYMX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50205789   

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50205789((E)-5-(4-fluorostyryl)-2-(4-fluorophenylsulfonyl)p...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50205789((E)-5-(4-fluorostyryl)-2-(4-fluorophenylsulfonyl)p...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50205789((E)-5-(4-fluorostyryl)-2-(4-fluorophenylsulfonyl)p...)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50205789((E)-5-(4-fluorostyryl)-2-(4-fluorophenylsulfonyl)p...)
Affinity DataKi: >4.00E+3nMAssay Description:Displacement of [3H]mesurgeline from human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed