BDBM50205666 CHEMBL247266::N,N-diethyl-3-(8-(4-methoxyphenyl)-5,6,7,8-tetrahydro-2,6-naphthyridin-3-yloxy)propan-1-amine

SMILES CCN(CC)CCCOc1cc2CNCC(c3ccc(OC)cc3)c2cn1

InChI Key InChIKey=SPBSCPKJFSEOAQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50205666   

TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205666(N,N-diethyl-3-(8-(4-methoxyphenyl)-5,6,7,8-tetrahy...)
Affinity DataKi:  23nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205666(N,N-diethyl-3-(8-(4-methoxyphenyl)-5,6,7,8-tetrahy...)
Affinity DataKi:  129nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205666(N,N-diethyl-3-(8-(4-methoxyphenyl)-5,6,7,8-tetrahy...)
Affinity DataKi:  226nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed