BDBM50205664 4-(3-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydro-2,6-naphthyridine::CHEMBL241705

SMILES COc1cccc(c1)C1CN(C)Cc2cc(OCCCN3CCCCC3)ncc12

InChI Key InChIKey=FINNTOGAVZWNGL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50205664   

TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205664(4-(3-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)...)
Affinity DataKi:  8nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205664(4-(3-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)...)
Affinity DataKi:  59nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205664(4-(3-methoxyphenyl)-2-methyl-7-(3-(piperidin-1-yl)...)
Affinity DataKi:  302nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed