BDBM50205647 4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-yl)methoxy)-2-methyl-1,2,3,4-tetrahydro-2,6-naphthyridine::CHEMBL392933

SMILES CC(C)N1CCC(COc2cc3CN(C)CC(c4ccc(Cl)c(Cl)c4)c3cn2)CC1

InChI Key InChIKey=HRDUUEDPDCVSJF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50205647   

TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205647(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  13nMAssay Description:Displacement of N-[3H]alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205647(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  23nMAssay Description:Binding affinity to rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50205647(4-(3,4-dichlorophenyl)-7-((1-isopropylpiperidin-4-...)
Affinity DataKi:  31nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed