BDBM50205352 CHEMBL3962283

SMILES CCc1ncc(cc1NC(=O)Cc1ccc(cc1)C(F)(F)F)C(=O)C1CC([C@@H](C)CO)c2ncncc12

InChI Key InChIKey=YATACVWKJZUENE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205352   

TargetHigh affinity nerve growth factor receptor(Human)
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50205352(CHEMBL3962283)
Affinity DataIC50: 13nMAssay Description:Inhibition of human TrkA expressed in human U2OS cells assessed as inhibition of NGF-induced response measured after 1 hr by beta-galactosidase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2018
Entry Details Article
PubMed