BDBM50205243 CHEMBL220321::N-(4-(2-(3-chloro-4-(cyclopropylmethylamino)phenoxy)thiazol-5-yl)but-3-yn-2-yl)acetamide

SMILES CC(NC(C)=O)C#Cc1cnc(Oc2ccc(NCC3CC3)c(Cl)c2)s1

InChI Key InChIKey=FARBKEHOFCZKSX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50205243   

TargetAcetyl-CoA carboxylase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205243(N-(4-(2-(3-chloro-4-(cyclopropylmethylamino)phenox...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant ACC2 expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50205243(N-(4-(2-(3-chloro-4-(cyclopropylmethylamino)phenox...)
Affinity DataIC50: 4.25E+3nMAssay Description:Inhibition of human recombinant ACC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed