BDBM50205088 2-((3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)(benzyl)amino)acetic acid::CHEMBL246270

SMILES Cc1oc(nc1CCOc1cccc(CN(CC(O)=O)Cc2ccccc2)c1)-c1ccccc1

InChI Key InChIKey=QXVPRNBTJIQOSJ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50205088   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205088(2-((3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benz...)
Affinity DataIC50: 90nMAssay Description:Displacement of fluorescein labeled ligand from PPARalpha receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205088(2-((3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benz...)
Affinity DataIC50: 240nMAssay Description:Displacement of fluorescein labeled ligand from PPARgamma receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205088(2-((3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benz...)
Affinity DataEC50:  295nMAssay Description:Agonist activity at PPARgamma receptor expressed in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50205088(2-((3-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benz...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at PPARalpha receptor expressed in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed