BDBM50204678 CHEMBL3931889

SMILES COc1ccccc1-c1cc(CN(C)C)ccc1Cl

InChI Key InChIKey=GROYHNLGVCIQOI-UHFFFAOYSA-N

Data  13 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50204678   

Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataEC50:  1.15E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human 5-HT7R transfected in HEK293 cells assessed as Gs-mediated cAMP accumulation incubated for 30 mins by microplate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataEC50:  479nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataEC50:  480nMAssay Description:Agonist activity at 5-HT7R (unknown origin) transfected in HEK293 cells expressing tTA-dependent luciferase reporter and beta arrestin 2-TEV fusion g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  11nMAssay Description:Binding affinity to 5-HT2BR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  20nMAssay Description:Displacement of [3H] D-lysergic acid diethylamide from 5-HT7R (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by microbeta scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  20nMAssay Description:Displacement of [3H] D-lysergic acid diethylamide from 5-HT7R (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by microbeta scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  220nMAssay Description:Binding affinity to 5-HT5AR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  270nMAssay Description:Binding affinity to 5-HT2CR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  360nMAssay Description:Binding affinity to 5-HT2AR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  440nMAssay Description:Binding affinity to 5-HT6R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  830nMAssay Description:Binding affinity to 5-HT1BR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to 5-HT3R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity to 5-HT1DR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity to 5-HT1AR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50204678(CHEMBL3931889)
Affinity DataKi:  4.10E+3nMAssay Description:Binding affinity to 5-HT1ER (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed