BDBM50204512 2-(7-phenylheptanoyl)oxazole-5-carbonitrile::CHEMBL220770

SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)C#N

InChI Key InChIKey=JOWNZAGZZQQDKI-UHFFFAOYSA-N

Data  6 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50204512   

TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataIC50: 20nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataIC50: 7nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataIC50: 20nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataIC50: 20nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataKi:  1nMAssay Description:Inhibition of human FAAH expressed in COS7 cells by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed