BDBM50204401 (3S,4S)-N-hydroxy-1-isobutyl-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)pyrrolidine-3-carboxamide::CHEMBL392312

SMILES CC(C)CN1C[C@@H](NC(=O)c2ccc(Cc3cc(C)nc4ccccc34)cc2)[C@H](C1)C(=O)NO

InChI Key InChIKey=VMWZNZVYBAZMKQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50204401   

TargetMatrix metalloproteinase-9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204401((3S,4S)-N-hydroxy-1-isobutyl-4-(4-((2-methylquinol...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204401((3S,4S)-N-hydroxy-1-isobutyl-4-(4-((2-methylquinol...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204401((3S,4S)-N-hydroxy-1-isobutyl-4-(4-((2-methylquinol...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204401((3S,4S)-N-hydroxy-1-isobutyl-4-(4-((2-methylquinol...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204401((3S,4S)-N-hydroxy-1-isobutyl-4-(4-((2-methylquinol...)
Affinity DataIC50: 220nMAssay Description:Inhibition of TACE in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204401((3S,4S)-N-hydroxy-1-isobutyl-4-(4-((2-methylquinol...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed