BDBM50204379 CHEMBL388982::N-hydroxy-2-[N-sec-butyloxy(4-methoxyphenyl)sulfonamido]-3-methylbutanamide

SMILES CCC(C)ON(C(C(C)C)C(=O)NO)S(=O)(=O)c1ccc(OC)cc1

InChI Key InChIKey=UZLNTZNPSMNCRL-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50204379   

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204379(N-hydroxy-2-[N-sec-butyloxy(4-methoxyphenyl)sulfon...)
Affinity DataIC50: 286nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204379(N-hydroxy-2-[N-sec-butyloxy(4-methoxyphenyl)sulfon...)
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204379(N-hydroxy-2-[N-sec-butyloxy(4-methoxyphenyl)sulfon...)
Affinity DataKi:  9.20E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204379(N-hydroxy-2-[N-sec-butyloxy(4-methoxyphenyl)sulfon...)
Affinity DataKi:  9.60E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204379(N-hydroxy-2-[N-sec-butyloxy(4-methoxyphenyl)sulfon...)
Affinity DataKi:  9.70E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed