BDBM50204376 2-{benzyloxybenzyloxy[(4-methoxyphenyl)sulfonyl]amino}-N-hydroxyacetamide::CHEMBL228176

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)OCc1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=PJOVXZAUKZMBRM-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50204376   

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204376(2-{benzyloxybenzyloxy[(4-methoxyphenyl)sulfonyl]am...)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204376(2-{benzyloxybenzyloxy[(4-methoxyphenyl)sulfonyl]am...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204376(2-{benzyloxybenzyloxy[(4-methoxyphenyl)sulfonyl]am...)
Affinity DataKi:  95nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204376(2-{benzyloxybenzyloxy[(4-methoxyphenyl)sulfonyl]am...)
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204376(2-{benzyloxybenzyloxy[(4-methoxyphenyl)sulfonyl]am...)
Affinity DataKi:  8.70E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed