BDBM50203991 (+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophenyl)-2-(1-isopropylpiperidin-4-yl)ethyl]piperazine tri hydrochloride::CHEMBL541897

SMILES CC(C)N1CCC(CC1)C(CN1CCN(CCCc2ccccc2-c2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=PSEZXKUUBYWUDL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50203991   

TargetTransporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 1.18E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 953nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 423nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 19.7nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203991((+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophen...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed