BDBM50203946 (R)-N-(2,3-dimethylbenzyl)-N-(pyridin-2-ylmethyl)pyrrolidin-3-amine::CHEMBL392016

SMILES Cc1cccc(CN(Cc2ccccn2)[C@@H]2CCNC2)c1C

InChI Key InChIKey=CHDGVSNCSOCUHK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50203946   

TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203946((R)-N-(2,3-dimethylbenzyl)-N-(pyridin-2-ylmethyl)p...)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50203946((R)-N-(2,3-dimethylbenzyl)-N-(pyridin-2-ylmethyl)p...)
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]NA from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203946((R)-N-(2,3-dimethylbenzyl)-N-(pyridin-2-ylmethyl)p...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]5-HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed