BDBM50203942 (R)-N-(2,3-dichlorobenzyl)-N-(cyclopropylmethyl)pyrrolidin-3-amine::CHEMBL395931

SMILES Clc1cccc(CN(CC2CC2)[C@@H]2CCNC2)c1Cl

InChI Key InChIKey=MDQSOSLERPCADB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50203942   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203942((R)-N-(2,3-dichlorobenzyl)-N-(cyclopropylmethyl)py...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]5-HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50203942((R)-N-(2,3-dichlorobenzyl)-N-(cyclopropylmethyl)py...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]NA from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203942((R)-N-(2,3-dichlorobenzyl)-N-(cyclopropylmethyl)py...)
Affinity DataIC50: 44nMAssay Description:Inhibition of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed