BDBM50203939 (S)-N-(2,3-dichlorobenzyl)-N-(pyridin-2-ylmethyl)pyrrolidin-3-amine::CHEMBL391806

SMILES Clc1cccc(CN(Cc2ccccn2)[C@H]2CCNC2)c1Cl

InChI Key InChIKey=KQOBDZDVQFUADH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50203939   

LigandPNGBDBM50203939((S)-N-(2,3-dichlorobenzyl)-N-(pyridin-2-ylmethyl)p...)
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]NA from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203939((S)-N-(2,3-dichlorobenzyl)-N-(pyridin-2-ylmethyl)p...)
Affinity DataIC50: 122nMAssay Description:Inhibition of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203939((S)-N-(2,3-dichlorobenzyl)-N-(pyridin-2-ylmethyl)p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50203939((S)-N-(2,3-dichlorobenzyl)-N-(pyridin-2-ylmethyl)p...)
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]5-HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed