BDBM50203653 CHEMBL3896657

SMILES OC(=O)CCc1cc2cc(ccc2o1)-c1cc(OC(F)(F)F)ccc1F

InChI Key InChIKey=HTIVRXDQROURHF-UHFFFAOYSA-N

Data  6 IC50  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50203653   

TargetCytochrome P450 2D6(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataEC50:  1.83E+3nMAssay Description:Agonist activity at human GPR40 measured after 60 mins by IP1-HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human GPR120 expressed in CHOK1 cells measured after 60 mins by IP1-HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataEC50:  43nMAssay Description:Agonist activity at mouse GPR120 expressed in CHOK1 cells measured after 60 mins by IP1-HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataIC50: 3.83E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human GPR120 assessed as induction of IP1 accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR120 assessed as induction of beta-arrestin recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataEC50:  43nMAssay Description:Agonist activity at mouse GPR120 assessed as induction of IP1 accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataEC50:  1.83E+3nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human GPR120 assessed as induction of IP1 accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR120 assessed as induction of beta-arrestin recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed