BDBM50203586 CHEMBL400047::diethyl {4-[(2R,10'S,11'S,15'S,17'R)-15'-methyl-3-methylidene-5'-oxospiro[oxolane-2,14'-tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecane]-1',6'-dien-17'-yl]phenyl}phosphonate

SMILES CCOP(=O)(OCC)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22OCCC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12

InChI Key InChIKey=NVKFRYWNCLQAGR-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50203586   

TargetProgesterone receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50203586(diethyl {4-[(2R,10'S,11'S,15'S,17'R)-15'-methyl-3-...)
Affinity DataIC50: 9.90nMAssay Description:Antagonist activity at progesterone receptor expressed in human T47 cells assessed as blockade of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50203586(diethyl {4-[(2R,10'S,11'S,15'S,17'R)-15'-methyl-3-...)
Affinity DataKi:  56.3nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed