BDBM50203528 (6S,7S)-N-hydroxy-5-methyl-6-[(4-phenyl-3,6-dihydropyridin-1(2H)-yl)carbonyl]-5-azaspiro[2.5]octane-7-carboxamide::CHEMBL219105

SMILES CN1CC2(CC2)C[C@@H]([C@H]1C(=O)N1CCC(=CC1)c1ccccc1)C(=O)NO

InChI Key InChIKey=YCCUTKPNUYYNML-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50203528   

TargetMatrix metalloproteinase-9(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50203528((6S,7S)-N-hydroxy-5-methyl-6-[(4-phenyl-3,6-dihydr...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50203528((6S,7S)-N-hydroxy-5-methyl-6-[(4-phenyl-3,6-dihydr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50203528((6S,7S)-N-hydroxy-5-methyl-6-[(4-phenyl-3,6-dihydr...)
Affinity DataIC50: 160nMAssay Description:Inhibition of Her2 sheddase activity in BT474 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50203528((6S,7S)-N-hydroxy-5-methyl-6-[(4-phenyl-3,6-dihydr...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50203528((6S,7S)-N-hydroxy-5-methyl-6-[(4-phenyl-3,6-dihydr...)
Affinity DataIC50: 77nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50203528((6S,7S)-N-hydroxy-5-methyl-6-[(4-phenyl-3,6-dihydr...)
Affinity DataIC50: 64nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed