BDBM50203483 4,5,6,7-tetrafluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)isoindoline-1,3-dione::CHEMBL243690

SMILES CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)N1C(=O)c2c(C1=O)c(F)c(F)c(F)c2F

InChI Key InChIKey=GFECFRLDYQFMGJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50203483   

TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203483(4,5,6,7-tetrafluoro-2-(4-(4-(2-isopropoxyphenyl)pi...)
Affinity DataKi:  30.2nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha-1d receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203483(4,5,6,7-tetrafluoro-2-(4-(4-(2-isopropoxyphenyl)pi...)
Affinity DataKi:  37.8nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha-1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203483(4,5,6,7-tetrafluoro-2-(4-(4-(2-isopropoxyphenyl)pi...)
Affinity DataKi:  4.11E+3nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha-1b receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed