BDBM50203482 4-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-yl)cyclohexyl)isoindoline-1,3-dione::CHEMBL243694

SMILES CC(C)Oc1ccccc1N1CCN(CC1)C1CCC(CC1)N1C(=O)c2cccc(F)c2C1=O

InChI Key InChIKey=DXHONOPMEUDNFH-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50203482   

TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203482(4-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  1nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha-1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203482(4-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  1nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha-1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203482(4-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  14.9nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha-1d receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203482(4-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  14.9nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha-1d receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203482(4-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  127nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha-1b receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50203482(4-fluoro-2-(4-(4-(2-isopropoxyphenyl)piperazin-1-y...)
Affinity DataKi:  127nMAssay Description:Displacement of [125]HEAT from human adrenergic alpha-1b receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed